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Accordingly, some key encryption methods or hash-based methods are exploited to solve this problem.
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We could use either symmetric encryption or a hash-based message authentication code (HMAC) defined below.
In this paper, we propose a method that can accelerate hash-based genome mapping by reducing the number of hash references without increasing the size of the hash table.
However, as the existed hash-based methods all focus on how to compress the existed handcrafted features into binary codes, their performance is limited by the utilized features and the information loss in the compression process.
The hash-based methods prepare a hash table whose keys and values represent subsequences of length l cut from a target genome and the subsequence genome positions, respectively.
The control of uniqueness described here can be exchanged for a suffix array approach [32], if the hash-based method raises memory-limit problems.
We propose a hash-based method for genome mapping that reduces the number of hash references for finding mismatches without increasing the size of the hash table.
The proposed naming scheme makes the best use of the features offered by hierarchical as well as hash-based or flat naming schemes.
These are classified into two categories according to their algorithms, which are either hash-based or suffix array/Burrow–Wheeler transition (BWT -based [ 3], MAQ [ 4] and SOAPv1 [ 5] are two hash-BWT -basedrithms.
The parameters governing the hash formation process, as well as the hash-based SI generation method used to create the initial version of the SI at the decoder, are identical to the configuration used in[11].
DRAGEN's hash-based mapping uses a novel dynamic seed extension method: when a primary seed (default 21 nt) matches more than a maximum number of reference locations (default 16), longer seeds from all these reference positions are populated into the hash table, such that specific extended seed sequences will match fewer reference locations.
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