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Indeed, several other constraints, e.g. costs of edge deployment and maintenance, capacities, weights (see Materials and Methods), or different routing strategies should be taken into account for more precise and system specific analysis.
These conflicting results might be due to different analysis methods or different gene sequence selection.
They often suffer, however, from poor quality, be it due to different sampling methods or different taxonomic resolution.
Therefore, either more powerful methods or different approaches will be needed to address the task of assigning sequences to species or taxa.
Although we assume that most laboratories used immunohistochemistry assays and consistent cutoff points, it is possible that some laboratories used different methods or different cutoff points.
The incongruence between molecular trees obtained with different methods or different data sets is also frequently encountered [ 23, 24] Studies on several other systems reveal similar uncertainty as we observed in our analysis [ 25, 26].
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Summary: Recently, several methods for analyzing phenotype data have been published, but only few are able to cope with data sets generated in different studies, with different methods, or for different species.
We do not limit the definition of "mixed methods" to the combination of quantitative and qualitative approaches and we consider that the use of different quantitative methods together, or different qualitative methods, could also be described as "mixed method" if they are used in the same project to study the same phenomenon or different aspects of the same phenomenon.
Improved fixation method or different localization to avoid accidental sensor removal.
To rank indicators with respect to their importance and enhance the transparency of the quality of care assessment, several approaches can be applied such as a survey, a Delphi method or different variants of conjoint analyses.
But it is hard to conduct a meta-analysis if only a few studies exist, or when those that do exist use different methods or measure different variables.
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