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Overall, 91% (609 out of 666, Additional file 2, Spreadsheet 1 & 2) of SVs had supporting evidence by retrospectively applied sequencing-based methods or database entries.
In case-control studies, cases had to be defined as patients with new onset pneumonia identified through clinical examination, radiological methods, or database codes.
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Currently, the transcriptome data that contain both lncRNA and protein-coding genes are rapidly increasing due to the dramatic advances in RNA-Seq techniques, and several methods or databases have also been developed to fill this gap.
Prior studies have attempted to validate adverse drug event codes in administrative data by comparing adverse drug event reports in administrative data to events identified by chart review, using electronic trigger methods or between administrative databases [ 36- 41].
This is not true and needs to be qualified: there are many papers about eukaryotes and several about either methods to detect or databases of detected promotors in various groups of bacteria, some of which have been obtained using intergenomic conservation as one of the criteria.
Other studies evaluating adherence to tamoxifen, using self-reported evaluation or database claim methods, found adherence rates ranging from 65%to85%5% for different periods of follow-up [ 13, 26- 29].
It can be argued (and often is) that Access is also a relational database, Microsoft certainly says it is, but the way the engine is built actually makes it an 'Indexed Sequential Access Method (ISAM)' database or a flat file database.
Overall, 609 out of 666 (90%) variants were supported by experimental orthogonal methods or historical evidence in public databases.
Methods using database searches may be roughly classified into two categories, depending on whether or not they provide E-values (or P-values) for candidate peptides.
Another key difference between our method and other database methods is that we do not need to limit the number of enzymatic miscleavages.
As these methods retrieve database information through a predefined series of scaffolds, the resulting cluster is structurally homogeneous.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com