Using this robust method of sensitization, all pigs in the control group developed severe allergic skin reactions and moderate to severe respiratory responses, similar to asthma, upon dermal or aerosol allergen challenge, respectively.
Because adsorption of PstS1 to L-particles has previously been described as very efficient in inducing specific cellular immunity to this antigen [ 29], we adopted this method of sensitization for our treatment protocol.
The results of in vivo animal testing for MMA skin sensitization are presented in Table 3, which shows the test species, test methods for induction and elicitation of sensitization, the vehicle used for induction and elicitation, and the test results described by the individual authors.
Various, efficient methods of the CP-MCL film sensitization towards calcium, magnesium as well as copper, cadmium, lead or zinc cations are presented.
This paper is dedicated to the establishment of experimental conditions for practical use of Double Loop Electrochemical Potentiodynamic Reactivation method (DL-EPR) to characterize the degree of sensitization in AISI 304 austenitic stainless steel based in the standard ISO 12732.
The development of an animal model system provides a method for the investigation of possible mechanisms of sensitization.
For instance, the use of less sensitive techniques such as complement-dependent cytotoxicity (CDC) crossmatch assays in comparison with more sensitive methods as solid-phase assays will result in lower rates of sensitization [ 2].
The method assumes that LNC proliferative responses are causally and quantitatively associated with the effectiveness of sensitization induction (ECETOC, 2003, 2008), yielding results that quantitatively describe relative sensitizing potency, which correlates with human sensitization thresholds (Loveless et al., 2010; van Loveren et al., 2008).
Momeni et al. (2010) obtained the optimal condition for the degree of sensitization (DOS) measurement based on double-loop EPR technique in H2SO4-containing KSCN solution by Taguchi method.
