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In all facilities, the same person (MW) explained the detailed methods of probing inspections to all investigators and confirmed reproducibility and consistency for each investigator.
We therefore designed a further experiment to test whether the different methods of probing at retrieval might have led to the different results between the experiments.
The two most commonly used methods of probing the metabolome are: mass spectrometry (MS) and proton nuclear magnetic resonance (H NMR).
However, given the orthogonal nature of these diverse methods of probing genome organization, it is difficult at this stage to firmly establish either direct structural or functional links between the genome-wide ensemble studies and our observation of enhancer clustering by single molecule imaging.
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Their approach, copied from the great chemist Linus Pauling, then at the California Institute of Technology, was to build exact scale models of the DNA that would be compatible with the limited information available from X-ray crystallography, a method of probing a chemical's structure with X-rays.
Neutron radiography is a powerful method of probing the structure of materials based on attenuation of neutrons.
Despite ultrasound having been demonstrated as a method of probing the internal structures of teeth more than 40 years ago, development of a clinical tool has been slow.
The results show that the ultra-microelectrodes offer a simple and reliable method of probing the solution composition under conditions where large area electrodes cannot be used.
We provided a method of probing 3D structure in its native form over time and linking matrix dynamics with cellular organization and function using graph theory.
An alternative method of probing conformational differences involves denaturation of PrPSc in increasing concentrations of guanidine hydrochloride (GdnHCl) [ 9].
A common method of probing the structure of these materials is extended X-ray absorption fine structure (EXAFS).
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