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By the beginning of the 19th century, the structure of the human body was almost fully known, due to new methods of microscopy and of injections.
Species-specific identification, which is relevant for the complex of different toxins production, by traditional methods of microscopy is difficult due to the high morphological variability, and thus different morphotypes can be easily misinterpreted.
Due to the frequent coiling of their structure, the usual methods of microscopy fail to give precise quantitative information about their dynamics.
Using different methods of microscopy, immunolabelling and a number of molecular markers, we describe the neural and mesodermal structures of the pygidium of Platynereis dumerilii.
Next we confirmed that azithromycin was inhibiting merozoite invasion directly, rather than acting on growth downstream of invasion, through the complementary methods of microscopy and flow cytometric quantification of ring-stage parasites at the time-point of 1 hour post-invasion.
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It is very important to note that these experiments are just preliminary proof-of-concept examples to test the abilities of the system and introduce a new method of microscopy.
Taxonomy of the Ostreopsis species based only on morphological characteristics is rather controversial due to the high morphological variability of both natural populations and cultured specimens [17] and therefore, species-specific identification by traditional method of microscopy is extremely difficult.
The methods of optical microscopy, electron microscopy, X-ray crystallography, and nuclear magnetic resonance increasingly are being combined in hybrid method approaches to achieve an integrated view of macromolecular complexes that span from cellular context to atomic detail.
In the 19th and 20th centuries, new techniques were developed for the study of plants, including methods of optical microscopy and live cell imaging, electron microscopy, analysis of chromosome number, plant chemistry and the structure and function of enzymes and other proteins.
In contrast to conventional methods of optical microscopy based on the registration of light intensity distribution, the laser interference microscopy allows obtaining the phase distribution in the interference image.
Kinetics of network formation is investigated by methods of polarization microscopy and integrated small-angle scattering.
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