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They may, according to Dr Ioannidis, be giving both false negatives and false positives about whether or not publication bias exists in a particular body of studies.Dr Ioannidis plans to run tests on the methods of meta-research itself, to make sure he and his colleagues do not fall foul of the very criticisms they make of others.
Several methods of meta-analysis have been suggested [ 1- 5].
All widely used methods of meta-analysis are of this type [ 3].
The results obtained from separate trials were combined using appropriate methods of meta-analysis.
We then applied three different methods of meta-analysis to derive gene signatures from the compendium.
To identify these signatures more rigorously we applied two methods of meta-analysis.
Table 4 (see additional file: Table 4) is a brief overview of the features of these articles as they relate to methods of meta-analysis.
Even though the methods of meta-synthesis are highly variable, qualitative meta-syntheses play a growing role in improving the understanding of patients' perspectives [ 14].
Implementation of these and other methods of meta-analysis identified gene-expression signatures associated with different aspects of tumorigenesis, including prostate tumorigenesis [ 6, 9- 13].
We aimed to build on the methods of meta-ethnography and explore the challenges of including a large number of qualitative studies.
In this case, from various methods of meta-synthesis, we determined the meta-ethnography with its interpretive orientation, to be the best approach.
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CEO of Professional Science Editing for Scientists @ prosciediting.com