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Applying the methods of genomics research to these diseases is one way to address this imbalance.
Fortunately, modern methods of genomics have recently produced an unprecedented amount of expression data from normal and cancer-associated tissues.
Martha Herbert, a pediatric neurologist at Harvard Medical School, and her colleagues have been applying the methods of genomics to identify environmentally responsive genes that might be important in these disorders.
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It is not purported to model the ancestor, even though it, same as the ancestral genomes, may be constructed using methods of comparative genomics, and even though minimal genome may be enriched in ancestral genes.
In the post-genomic era several methods of computational genomics are emerging to understand how the whole information is structured within genomes.
Our curation method verified unique paired read placement throughout the reconstructed genomes, a requirement consistent with standard methods of isolate genomics.
An individual genome contains evidence of the niche to which it is adapted, which we can study using the methods of comparative genomics.
On the other hand, both high-throughput methods of functional genomics and traditional molecular biology routinely generate timecourse data, where dynamic changes in relative molecular activity after perturbation are monitored.
It is uncertain as to how many more are 'common' and are to be found via the methods of structural genomics, but many have been expertly classified, e.g. in the CATH, SCOP or InterPro databases, and do occur repeatedly.
Although whole-genome sequencing is a powerful method of genetics and genomics, it is still laborious and expensive.
According to Valencia, the job that Al-Shahrour does requires a very wide range of knowledge and skills; he emphasizes her "biological background, capacity to develop bioinformatics methods, deep understanding of genomics, good communication skills and proved record in team management".
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