Sentence examples for methods of differentiation from inspiring English sources

Those that avoid sticking to the old tried and true methods of differentiation that worked in the past will be light years ahead as the transformation of healthcare takes hold.

Accordingly, the growth factor-driven cell fate choices methods of differentiation described here provide an opportunity to study the molecular mechanisms controlling cell fate specification of pluripotent cells equivalent to early stages of human and mouse embryonic development.

Of equal interest are the species strongly induced with both methods of differentiation, which include SFRP4, PITX2 and WNT2B.

Our methods of differentiation provide an advantageous system to model early human endoderm development in vitro, and also represent an important step towards the generation of pancreatic and hepatic cells for clinical applications.

We chose this differentiation model since, unlike most other methods of differentiation that generate heterogeneous mixtures of many different cell types from all three germ layers, Oct4 KD robustly induces trans-differentiation to trophectoderm specifically [ 50].

Finally, we also applied this protocol to hIPSCs resistant to conventional methods of differentiation and observed that chemical inhibition of CDK4/6-cyclin Ds significantly improved the capacity of these lines to differentiate into endoderm derivatives thereby allowing the generation of pancreatic and hepatic cells.

By the method of differentiation of these curves, a large number of deep levels were found.

Kondo et al. (Kondo et al., 2014) developed a simple method of differentiation of human iPSCs into functional HLCs with small-molecule compounds, which are convenient and inexpensive to obtain for large scale production and do not have the potential to be contaminated with exogenous viruses or cells.

It should now be possible to apply this method of differentiation to neurons derived from induced pluripotent stem cells (iPSCs) from patients with tau pathologies and Tau gene mutations and to use these neurons for the screening of compounds to prevent tau dysfunction.

9 30 31 None resulted in a suitable method of differentiation, with most of the studies being retrospective with small numbers of patients.

The lack of labelling by antibody P4 is a recognised method of differentiation between ovine BSE and scrapie derived PrPres [ 23].