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The generality of the improved formulas is verified via the statistical methods of bootstrapping and cross-validation.
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We used the method of bootstrapping (sample = 200) to generate t-statistics to test the significance levels of standardized path estimates.
This method allows the measuring of the indirect effect that represents the impact of the mediator variable on the stipulated relation by a method of bootstrapping (10000) with confidence intervals.
The Support Tree method of bootstrapping implemented in TMEV was used to test the reliability of the clustering patterns (1,000 bootstrap resamplings).
The Support Tree method of bootstrapping implemented in TMEV was used to test the reliability of the clustering patterns (500 bootstrap re-samplings).
When estimating the time-course GRN from the apoptosis time course microaray data, a method of bootstrapping was applied to the data.
43 The method of bootstrapping could not be implemented while accounting for complex survey design in Stata by first-order Taylor linearisation; however, comparison of unweighted means with and without bootstrapping revealed very small differences.
Clustering of strains based on LR profile similarities was performed by the average linkage hierarchical clustering method [ 35], as implemented in TMEV, using Pearson correlation coefficient as a distance metric with the Support Tree method of bootstrapping implemented in TMEV used to test the reliability of the clustering patterns (500 bootstrap re-samplings).
For this reason, Sauerbrei and Schumacher [ 14] proposed the use of bootstrapping methods in combination with automatic backward selection.
In particular, the simultaneous fitting of prior and posterior odds of the disease could be considered complex, as could the use of bootstrapping methods to construct confidence intervals for coefficients.
However, as the architecture of MSVM-RFE uses simple bootstrapping, it naturally follows that utilizing another popular ensemble method, boosting [ 14], instead of bootstrapping for two reasons.
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