Sentence examples for methods of allele from inspiring English sources

We compared the UV classification methods of allele frequency, Polyphen, sequence conservation, and the GMS by examining the pairwise joint distribution of BRCA1/ BRCA2 UVs as classified using each method.

Because of the importance of more precisely determining the role played by HLA alleles in PsA, using improved PsA case ascertainment based on the Classification Criteria for Psoriatic Arthritis (CASPAR) [ 1] and more accurate methods of allele determination, we set out to compare the similarities and differences in the frequency of HLA-B and HLA-C locus alleles between PsO and PsA.

Therefore, to reduce any overestimation of rare alleles, we used a round-robin method of allele frequency estimation [ 51].

Allele-specific hybridization (ASH) is a method of allele discrimination in genotyping.

We use the quantitative polymerase chain reaction (qPCR) as our method of allele quantification, but any method that can reliably distinguish the difference between one and two copies of the target gene can be used to develop an LOA assay.

3 This method of allele targeting, although quick, bears several risks.

Allele detection was carried out using the MALDI-TOF mass spectrometry method of allele determination on a Sequenom platform.

There was a small change in α as a result of the round-robin method of allele frequency estimation (Additional file 2: Table S2).

The method of allele association has been quickly and productively applied in the area of multi-factorial mental illnesses for which genetic components have long been demonstrated by large heritability estimates.

The fingerprinting assay was tested using the MALDI-TOF mass spectrometry method of allele determination on a Sequenom platform with a panel of 28 Caucasian HapMap samples; the results were compared with known genotypes to ensure accuracy.

Approximately 5.5% of the genotypes were created with an in-house developed method of allele-specific primer extension on microarrays, as previously described [36].