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Despite more domains being defined manually for a single chain in contrast to automated methods, manual definition produced a marginally lower number of polypeptide segments per domain (fig 2b).
Of the three tested registration methods, manual registration was most accurate.
Detailed correlation analysis of the two segmentation methods (manual and automated) was also conducted by Bland-Altman analysis.
In vivo and ex vivo CT including histopathology were coregistered with three different methods (manual, semi−/automatic).
To this aim, samples were prepared with different binders (linseed oil and polyvinylalcohol), mixing methods (manual vs. sonication) and pigment volume concentration (PVC).
Figure 7a shows a sentence example of fundamental frequency generated from the Mixdorff methods, manual and automatic, and the methods presented in this paper, tonal and lexical.
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The NBHW guideline development process follows a transparent methodology (documented in methods manuals) that states how evidence should be collected, assessed and transformed into recommendations.
Table 2 Average CPU time of methods Method Manual segmentation Watershed PolarSnake GaborFM Average CPU time (s) About 80 19.98045.49 10.80.
The current medfly weekly monitoring method, manual counting, results in a suboptimal spraying frequency in citrus orchards.
Libraries were then created following standard procedures from the Roche Paired End Library Preparation Method Manual.
The 4 resulting bead libraries were sequenced on a Roche GS-FLX system following the GS FLX Titanium Sequencing Method Manual (version October 2008).
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