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The unique strength of SMRT technology relative to other next-gen sequencing methods is single-molecule reads that exceed 10 kb in length.

The top-5 methods are single resolution methods which generate one partition.

An additional method is Single Genome Amplification in which viral RNA is extracted from a sample and copied into cDNA, which in turn is subjected to limiting dilution and PCR amplification.

These methods are single-step and the update operation is only a single rotation.

Other methods are single-pass, storing summaries of past data as they are scanned [25].

Note that since all the methods are single-copy routing schemes, average path length corresponds to average transmission count.

The proposed multimode method is single-parameter, non-iterative and offers simplicity, automaticity and robustness.

Similar to the rotation assay, our method is single-cell based and permits the study of behaviors of individual cells as well as the average behavior in a population.

This method is single-point analysis.

An alternative method is single-molecule PCR (Kraytsberg & Khrapko, 2005).

The method is single-chip based, i.e. it separately uses the intensities for each selected chip.

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