Sentence examples for methods generally fail from inspiring English sources

Unfortunately, these methods generally fail to reproduce experimental thermodynamic response (i.e., excess heat capacity profiles).

The linear algebraic systems (Jacobians) are sparse, nonsymmetric and indefinite, for which standard linear system solvers based on Krylov subspace methods generally fail to converge without appropriate preconditioners.

The rest of the residues are modeled with large errors because the homology modeling methods generally fail to model structural distortions and rigid body shifts, and are unable to recover from misalignments [25] [27].

The inverse problem is highly sensitive to measurement noise, and the classical pseudo-inverse method generally fails to find the correct loads.

Despite progress in secondary structure modeling, high-throughput methods have generally failed to determine ncRNA tertiary structures, even at the 1-nm resolution that enables visualization of how helices and functional motifs are positioned in three dimensions.

Powerful global modal reduction techniques have received growing recognition towards significant performance gain in physical simulation, yet such numerical methods generally will fail when handling deformation of heterogeneous materials across multiple sub-domains involving cutting simulation.

Despite anecdotal success, conventional methods and combinatorial drug screens generally fail to come up with effective combinations due to the genomic complexity and heterogeneity of tumors (Zhao et al., 2014).

Even when we are able to differentiate species within these clades using a character-based approach (i.e., accepting any single nucleotide difference), genetic diversity is extremely low and methods based on genetic distances generally fail to distinguish close relatives even when these show clear-cut morphological and geographical differences.

Indeed, the argument for separate treatment fails for the same reason that the arguments against same-sex marriage generally fail.

These three explanations generally fail to pass empirical tests.

However, current bioreactor designs generally fail to produce physiological relevant frequency and strain values.