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These include methods for unique molecular identifiers and sequencing error correction, V(D J assignment and detection of novel alleles, clonal assignment, lineage tree construction, somatic hypermutation modeling, selection analysis, and analysis of stereotyped or convergent responses.
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Other optimization steps expected to increase the output of CRoPS further include selection against plastid (chloroplast sequences) co-isolated with genomic DNA, the use of normalized genomic or cDNA [28] libraries or other methods of enrichment for unique, single-copy sequences such as High Cot selection [15] or methylfiltration [16], prior to AFLP amplification.
In other words, uniqueness of an identifier requires a method for assigning unique, canonical, numbers to the atoms.
A new effective method for designing unique gigantic polyfunctional macrocarbocycles from cyclic acetylenes and Grignard reagents through the catalytic cyclometalation reaction in the presence of transition metal based complexes has been elaborated.
Here we report the first molecular map of the maize B centromere and outline a method for assembling unique sequence from highly repetitive centromere regions.
Data integration was based on the OnPLS method for its unique features of handling complex multi-omic datasets, extracting global and locally joint variations from them and, thus, facilitating the acquisition of biological understanding.
Methods for producing such unique antigens are presented and preliminary test results reported.
Synthesis of anisotropic metal nanoparticles motivates the development and innovation of theoretical methods for describing the unique properties of these nanoparticles.
The results of this multidisciplinary systematic review examine the application of diagrams in data collection and the methods for analyzing the unique datasets elicited.
The results of this multidisciplinary systematic review provide an overview of the application of diagrams in research data collection and the methods for analyzing the unique datasets elicited.
We also obtained results that are very close to, and sometimes better than, those of the current state-of-the-art methods for the non-unique probe selection problem, namely integer linear programming and optimal cutting-plane approaches.
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CEO of Professional Science Editing for Scientists @ prosciediting.com