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To avoid segregation of transgenes, methods for targeted gene integration into the pre-determined genomic sites or gene stacking are needed.
Although many different methods for targeted capture have been described, only few have been extended to target the human exome.
Therefore tools and methods for targeted genome modifications are of great interest.
There is also a need to design novel methods for targeted delivery of these compounds into the middle ear, allowing higher therapeutic doses and minimizing systemic side effects.
Amplicon-based methods for targeted resequencing of cancer genes have gained traction in the clinic as a strategy for molecular diagnostic testing.
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Hybrid biological systems with integrated and targeted nanomaterials may have interesting and exploitable properties, so methods for targeting various nanomaterials to precise biological locations are required.
The demand for vulnerability maps among development agencies and governments is increasing as greater emphasis is placed on scientifically sound methods for targeting adaptation assistance.
Methods for targeting of small molecules to cellular proteins can allow imaging with fluorophores that are smaller, brighter, and more photostable than fluorescent proteins.
An Army spokesman, Paul Boyce, said Monday that the Army did not publicly discuss specific methods for "targeting enemy combatants," and that no classified program authorized the use of "drop weapons" to make a killing appear justified.
This paper studies the evaluation of methods for targeting the allocation of limited resources to a high-risk subpopulation.
She said improvements to the program since the reports were created included improved methods for targeting locations, and better culling efficiency and monitoring of the impact on coral cover.
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