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This study evaluated Somatosensory evoked potentials (SEP), Quantitative sensory testing (QST), and thermography as diagnostic methods for nerve injury.
Clearly, there is a strong need for establishing reliable methods for nerve substance defects in clinical practice.
Since the spatial distribution of the myelinated fibers are not uniform in human [ 25, 26] and animal nerves [ 27, 28] and pathological changes may be focal, multifocal, or diffuse in abnormal nerves, sampling methods for nerve morphometry have been investigated [ 26, 29], still with controversial conclusions.
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These limitations suggest a need for alternative methods for nerve-tissue repair.
Thus, we aimed to investigate the reproducibility of a semiautomated method for nerve morphometry between three observers with different levels of expertise and experience with the method.
The review emphasizes the urgent need for standardization or rationalization of animal models and evaluation methods for studying nerve repair.
However, the agreement between MRI and other diagnostic methods for detecting nerve involvement has not been fully evaluated.
Thermal perception thresholds were determined in 11 healthy overweight adult males using two methods for small nerve fibre functioning: a reaction-time inclusive method of limits (MLI) and a reaction time exclusive method of levels (MLE).
In this study we chose the simple yet thorough physical examination and pain drawing methods for detecting nerve involvement originating in the spine and for comparison with MRI findings.
Given that motor recovery is the most desirable outcome following peripheral nerve repair in humans, the present work provided significant evidence that the presence of Schwann cells improved the clinical efficacy of bilayer NGCs and that Schwann cell seeded bilayer NGCs possess significant potential as future methods for peripheral nerve repair.
Entubulization methods involving polymers where a conduit is used to connect the nerve endings has great potential as a repair method for peripheral nerve regeneration.
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