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Finally, we observed that LD-based refinement methods do not always outperform single site based methods for genotype calling.
As new methods for genotype imputation are developed, the relative performance of these methods must be assessed.
Several methods for genotype calling [ 10- 13] and assessment of copy number [ 14, 15] have been developed.
The most commonly used methods for genotype readout are based either on fluorescence or mass spectrometry (MS).
We provide access to the raw summary-level intensity data, allowing users to develop their own methods for genotype calling or copy number analysis if they wish.
Although the statistical methods for genotype imputation are now highly developed and widely used, there are still open questions in the field.
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PCR methods for genotyping the trichothecene chemotypes of Fusarium species were developed according to allelic variants of trichothecene biosynthesis genes in isolates with strain-specific chemotypes.
He predicts the company should benefit as doctors start demanding new gene-based diagnostic tests for their patients, such as new methods for genotyping the AIDS virus.
Despite previously published methods, there is still a lack of rapid and affordable methods for genotyping the Meyerozyma guilliermondii yeast species.
The biggest strength of DNA amplification-based methods for genotyping is their sensitivity: from a single DNA molecule, billions of DNA molecules are synthesized during amplification.
Conventional methods for genotyping CPV strains are labor intensive, expensive or time consuming; the present PCR-based HRM assay might be an attractive alternative.
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