Sentence examples for methods for array from inspiring English sources
The annotated information of the arrays, including normalized probe intensity, segmentation data and quality evaluation, was obtained from our arrayMap database [ 37] (see Methods for array processing pipeline).
They have shown translation invariant wavelets are promising methods for array CGH data smoothing and also observed that the denoising techniques may miss singleton clones that have small changes but somehow are consistent across tumors.
As a first step for our analyses, we assessed the quality of our human 9 K CGI array (see Methods for array construction) as well as the consistency of our labeling.
Owing to the plethora and complexity of methods for array processing and analysis, described above, and to the multitude of researchers using DNA methylation arrays, there is a need to create a protocol of good practice to ensure that study results are of the highest quality possible.
There is a need for improved statistical methods for array-based genotyping.
Based on this large data set with known truth, the authors have performed a comprehensive comparison of segmentation methods for array-CGH data based on receiver operator characteristic (ROC) curves.
Our aim is to help researchers understand the growing body of statistical methods for array-based DNA methylation data, focusing on those freely available in open-source environments such as R or Bioconductor (Table 1).
Scatter increases at low expression, which is not surprising, as background correction methods for arrays are complicated when signal levels approach noise levels.
Application of a measured PSF in beamforming analysis shows that the process provides an effective in situ method for array calibration both with and without flow and allows for corrections to incorporate reflections and scattering.
Furthermore, a novel normalisation and background estimation procedure for tiling arrays is presented along with a method for array analysis focused on detection of short transcripts.
CNVs were called using the Aberration Detection Method 2 (aDM2), a very broadly used CNV detection method for array CGH platform through GeneSpring Software.
