Sentence examples for methods for affinity from inspiring English sources

Free energy methods for affinity computation can include steric and electrostatic protein ligand interactions, solvent effects, and thermal fluctuations, but often they are computationally demanding and require a high level of supervision.

Improvements on the computational methods for affinity prediction from the structure of protein ligand complexes require a better understanding of the nature of molecular interactions and biomolecular recognition principles.

Such qualitative models may also be helpful for guiding the development of methods for affinity estimation.

Typical methods for affinity determinations such as surface plasmon resonance and ITC provide high quality information, but have limited throughputs.

With the development of high-throughput methods for identification of domain-motif interactions there is a need for high-throughput methods for affinity determination.

Next, pull-down methods for affinity-based analysis of protein protein and protein immobilized ligand interactions are discussed.

This could be an extremely attractive and versatile method for affinity enrichment of phosphorylated proteins.

The method for affinity purification of the mutant proteins was somewhat altered from the one previously used in order to minimize aggregation of EF-Tu and thereby improve TEV cleavage efficiency and avoid contamination by native EF-Tu.

We assess its performance against a protein protein binding affinity benchmark and show that both experimental methods used for affinity measurements and conformational changes have a strong impact on prediction accuracy.

A series of azinesulfonamides of long-chain arylpiperazine derivatives with semi-rigid alkylene spacer was designed, synthesized, and biologically evaluated using in vitro methods for their affinity for dopaminergic D2 and serotoninergic 5-HT1A, 5-HT6A, 5-HT7 and 5-HT7 receptors.

Screening phage-displayed combinatorial libraries represents an attractive method for identifying affinity reagents to target proteins.