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Different sequences of the chemotype retrieval indicate that the methods explore the chemspace in various directions.
DFT methods explore the information concerning the scattering region, transmission coefficient, electron current and non-equilibrium forces in the system [7, 8, 9, 10, 11].
Most of these methods explore the facts that substrates directly bind to the degradation machinery and/or substrates are ubiquitylated.
Sequence-based methods explore the sequence conservation in proteins under the assumption that ligand-binding site sequences are conversed in the evolution process.
Fragmentation tree methods explore the space of possible ways in which the metabolite can fragment, and base the metabolite identification on scoring of these fragmentation trees.
A common element is that global sensitivity methods explore the full parameter space, quantifying a model's sensitivity to perturbations in each parameter.
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For larger biological systems, even with enhanced sampling methods, exploring the free energy landscape remains computationally challenging.
Unlike classical test theory (CTT) which explores the difference between raw scores, Rasch analysis is one of the contemporary psychometric methods exploring the probability of an individual's response to an item.
Both methods explored the participants' knowledge and views towards breast screening, factors influencing uptake and views regarding the current format and organisation of screening for women over 70 years.
Hadamard conjugation has been used as both a tool for simulation [ 10] and to look at statistical properties of methods, exploring the inconsistency of parsimony under a molecular clock [ 5, 11].
For eleven sequences with 27 monomers, the proposed method explores the conformation surfaces more efficiently than other methods, and finds new lower energies in several cases.
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