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The model, on the other hand, following step-wise methods determines the parameters through an optimization procedure (with respect to the residual sum of squares at each step in the model) and the model refinement process takes care of possible combinations of parameter inputs thereby choosing the most influential parameters and corresponding functional forms.
As shown in Figure 4a-b, the HADB procedure (see methods) determines the distance from the peakMax to the point where the frequency of the top scoring motif approaches the distal flank motif frequency (distal = 250-500 bp from the peakMax).
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Integer Linear Programming (ILP) based methods determine the optimum mappings.
Finally, automatic methods determine the number of modules completely automatically, usually by iterating over several parameter settings and selecting the one that optimizes some criterion of cluster quality.
Previously described methods determine the proportion of predictable cases for blocks of equal lengths.
Therefore, both methods determine the same activity to deliver of 3.88 GBq.
These methods determine the threshold value from SAD values of blocks spatially and temporally adjacent to the current block.
Currently available methods determine the importance of genes in the pathway by a single measure.
Both methods determined the fewest genotypes in the non_par UCSC ROI region.
BAS, DC and MJP developed the study methods, determined the model settings and inputs, and contributed scientific advice.
We distinguish three different ways a method determines the number of modules (Fig. 2b).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com