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(DOC 190 KB) 13550_2011_13_MOESM2_ESM.DOC Additional file 2: Supplementary Figure 2: Individual input functions derived using the three methods, corrected for injected activity and aligned for peak activity.
Even after we had analysed the Unal data with more advanced statistical methods, corrected for factors like sex, age, education and aetiology, the reversed trend remained.
The genomic relationship matrices were computed as a weighted sum of the single-marker genomic matrices for each of the methods, corrected for mean identity by state (IBS) relatedness.
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The FiveEW method corrected for scatter and contamination while preserving the linearity of activity measurement (Fig. 7, Table 5).
P-values were corrected for multiple testing using the Bonferroni method (corrected for seven tests: one for each frequency band).
The Bonferroni method corrected for multiple comparisons.
Relative expression was determined using the ΔCt method corrected for primer efficiencies.
Confidence intervals were estimated using the efficient-score method corrected for continuity (Newcombe, 1998).
Two-sided 95% CIs for differences between groups were calculated based on the asymptotic method corrected for continuity, except for differences in subgroup analyses where the Wilson score method corrected for continuity was used.
We calculated 95% confidence intervals using an approximation (according to the efficient score method, corrected for continuity).
*Includes 2 CE patients with burns: 1 tigecycline cure and 1 comparator failure; †Calculated using asymptomatic method corrected for continuity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com