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All these methods consider only the fixed channel condition.
Unlike full time-domain simulation, the reduced methods consider only the active power-frequency dynamics to reduce computation burden.
Traditional static analysis methods consider only specific situations; they fail to adequately explain the mutual interactions between the operator and the reactor plant characteristics.
However, the methods consider only two variables at a time, which could be a big disadvantage for the complex system with more than two variables.
Purely local upscaling methods consider only those fine-scale grids that are combined in the target coarse-scale grid (Durlofsky 1991; King and Mansfield 1999).
However, the vast majority of these methods consider only specific classes of pharmaceuticals [38, 39] or compounds with similar polarities and/or use numerous extraction methods that are time-consuming and labor-intensive.
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In the P-GSTA method, a linear function with all significant granulometric parameters that are summed with different weighting factors was used to infer sediment-transport direction (sediment flux pattern); the previous grain-size trend analysis (GSTA) methods considered only three parameters (mean grain size, sorting, and skewness) with equal weighting.
Comparison of the flux sampling method to the best local and global topology methods considers only the enzymes present in the reduced model.
The approach may become more useful if better annotation methods (considering only GWA signals without interactions) can be adapted to epistasis.
Not all methods provided a quantitative estimate of validity and most methods considered only the positive predictive value of a set of diagnostic codes in a highly selected group of cases.
In summary, we believe that our approach of identifying subsets of signal pathways that associate with specific hallmarks of cancer represents a significant improvement over previous methods considering only specific gene ontologies or gene set enrichment.
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