Real-time RT-PCR is the most sensitive and specific method, but remains restricted to reference laboratories.
These techniques mitigate some of the challenges associated with conventional label-based methods, but sensitivity remains a key limitation and accurate characterization of high affinity aptamers remains difficult.
The intrauterine contraceptive device (IUD) is one of the most effective contraceptive methods, but it remains underutilized, especially among adolescents.
Current computing power enables the use of the computationally demanding listmode reconstruction methods, but it remains a challenge to keep track with the faster acquisition times (down to 1 min per bed position).
Venous cutdown is regarded as the method of last resort, but remains useful in emergency situations when other attempts at venous access have failed.
The detection of this kind of events is due to the method of identification of ICDS but remains however a minor inconvenience [ 3].
To facilitate communication, 32.6 % reported to regularly use augmentative and alternative communication methods, but the most effective and preferred method remains the use of basic gestures.
The consumption of methods videos remains modest compared with that of traditional, print-only journals.
Despite recent advancements in the treatment methods, prognosis remains poor.
At free energies better than about −15 kcal/mol the signal-to-noise ratio (S∶N, see Methods) remains above 1.5, but this ratio diminishes rapidly at higher free energies (Figure 2C,D).
