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These methods assume high correlation between coefficients, hence most of the pairs would not overflow even after expanding the difference.
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These methods often assume high per-marker accuracy, complex haplotype, and the availability of a reference genome.
Therefore, understanding the mechanisms associated with development of MPH addiction and designing methods to prevent it assume high public health significance.
For instance, class (I) methods assume that isolated high-resolution structural homologs of different parts of a given cryoEM are available in some databank, which is often not the case.
Proposed pooling methods can be limited because they generally assume high-quality genotypes derived from deep-coverage sequencing, which may not be available.
Among image segmentation methods, Hough transform requires a computational load which increases with the number of noise pixels, level set methods also require a high computational load, and some other methods assume that the contours are one-pixel wide.
Both methods assume a sufficiently small CFO and also a not high SNR so that the ICI is much smaller than the noise and can be ignored.
All these methods assume a certain degree of generality of the ceRNA hypothesis, and require some high-throughput expression data as input.
These methods assume that measurement errors vary independently over time.
These methods assume independent observations.
Most existing methods assume that data follow a Gaussian distribution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com