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Membrane FUGUE outperforms all other methods in all brackets, except at >35% sequence identity where the differences between the methods are marginal.
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For most sequences, improvement in the perception of DWE due to modified Gotsman's method is marginal.
We conclude that deep monitoring using the TS method is marginal at depths in the order of 4 km and that in order to have meaningful interpretations, electric field data need to be of a high quality with low levels of site noise.
For the 10 cases where our algorithm did not show the highest precision, the difference from the fractional method was marginal (Supplementary Table S3).
However, where the necessary dose-response functions already exist and impacts are marginal, the method can be very inexpensive to use with low demands on time, providing reasonable first approximations of true economic value.
The savings are marginal.
Conditions are marginal.
But these are marginal features.
Fringes are marginal, by definition.
Overall, the performance gain of this alternative approach over existing methods was rather marginal.
With sufficient data and under the necessary assumptions, the dynamic marginal structural model methods are unbiased, as we showed in simulations of very large observational studies (n = 100,000 participants).
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