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P is the correlation between I and C while controlling for P, where I denotes CGI, C denotes accumulated score (strength of predicted TFBS clusters, see Methods) and P denotes promoters.
Differential expression analysis was performed by pairwise comparison using linear models and empirical Bayes methods, and P values adjusted using the Benjamini and Hochberg's method to control for multiple testing.
Effects (tested allele effect on DNA methylation on transformed scale, see " Materials and methods") and P values are calculated using linear regression Four SNPs (rs12443878, rs12444338, rs62040565 and rs8060301) showing evidence to act as meQTLs in HYPEST and CADCZ analysis overlapped with SNPs genotyped or imputed in the EGCUT (Estonian Genome Center of the University of Tartu) sample set.
Let p0 be the initial vector showing the relevance of seeds to recombination hotspots (i.e., assigned by our prioritizing methods) and p t be a vector in which the i-th element shows the relevance of node i at step t.
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Phylogenetic analysis of KUW2010/02 Seg-3/VP3(T2), conducted by using neighbor-joining methods and p-distance matrices (12 ), showed nucleotide/amino acid identity levels of 73.7%/87.6%to76.6%/88.9%.9% with other BTVs.
The sequences were aligned using Clustal W Thompsonn et al. 1994) and analyzed using Neighbour-Joining method and p distance model.
A new intermediate refraction point (P_{1}^{prime }) is calculated between P 0 and P 2 using the dichotomy method, and P 1 is replaced by (P_{1}^{prime }).
P values for tumor growth were calculated by Kaplan-Meier Time to Progression method, and p values for two sample comparisons were calculated by two-sided Wilcoxon Rank-Sum test.
Models for use in OLS regression were selected using the backward elimination method, and p < 0.05 was considered statistically significant.
Serum creatinine (kinetic alkaline picrate method), Ca (cresolphthalein-complexone method), and P (ammonium molybdate method) levels were assayed by routine, standard colorimetric techniques using a routine analyser.
The results of BCR and VCC were subjected to two-way ANOVA and multiple comparison using the Bonferroni method, and P < 0.05 was regarded as significant.
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