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The responses can be categorised into four themes namely documentation of programme outcomes, implementation, understanding of the teaching & learning methods, and alignment of assessment and programme outcomes.
There is minimal loss of sensitivity or specificity with 2 × 75 cycle sequences when compared with 2 × 101 cycles using current library preparation methods and alignment and variant calling algorithms.
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Existing methods for measuring similarity/dissimilarity between DNA sequences roughly fall into two types: alignment-based methods and alignment-free methods.
However, support for these groupings is contingent upon analysis method and alignment strategy.
Indels were identified by the CUSP method and alignments were projected through a graphical viewer, StructView, described elsewhere [13].
Therefore, in addition to proposing a new method, we also present a large-scale numerical comparison of the performance of 10 genome tree inference methods, including 9 alignment-free methods and 1 alignment-based method.
For instance, the latest version of T-Coffee (Version 6.00) is able to combine up to 15 different alignment methods, including pair-wise structural aligners, regular multiple sequence alignment methods and even RNA alignment methods such as Consan (Dowell and Eddy, 2006).
The morphology and chemical structure of GMfs are investigated by various microscopic and spectroscopic methods and their alignment is dependent on the compositional variations.
These methods can be classified into two categories: sequence-sequence alignment methods and sequence-structure alignment methods [ 13].
From the start, the T-Coffee framework made it possible to turn any pair-wise method into a multiple alignment method, thus opening the way to two major developments undergone by multiple aligners these last years: meta alignment methods and template-based alignments.
> A total of 12,902 protein-coding genes were predicted using a combination of ab initio methods and transcript alignments.
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