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To assess the performance of this new methodology, we performed a comprehensive comparison of AmpliSeq with RNA-seq using two well-established next-generation sequencing platforms (Illumina HiSeq and Ion Torrent Proton).
As part of our methodology we performed two online surveys amongst a broad range of stakeholders and amongst monitoring professionals.
In this study, by means of experimental design methodology, we performed the first in-depth examination of the ways in which thawing conditions affect lipid metabolite levels.
Based on the amplified luminescent proximity homogeneous assay screen methodology, we performed high throughput screening and discovered a novel GCN5 inhibitor DC_G16 with 1,8-acridinedione scaffold.
To demonstrate the potential of our proposed methodology we performed quantitative comparisons of the efficiencies of different normalization and analysis methods.
To further validate the robustness of our dating methodology, we performed a simulation using only tip dates, without setting a prior for the root height of the tree.
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To further demonstrate the applicability of the methodology, we perform computational studies for spherical particles having translational and rotational degrees of freedom.
To estimate the fit of the demographic model obtained from different methodologies, we performed coalescence simulations using the program ms (Hudson 2002).
To compare the results of the WGP and SNaPshot methodologies, we performed a stepwise assembly (initial cut-off of 1e-75, 15 steps until a final cut-off of 1e-05) of the SNaPshot fingerprints from the 11,238 BACs clones used in WGP (see above).
In order to demonstrate the application of the methodology proposed, we performed some investigations in the design of a heater aimed to simulate the transport of heat and momentum in the core of a pressurized water reactor (PWR) at 100% of nominal power and non-accident operating conditions.
We considered a search result acceptable if less than 5% of the total articles of a specific journal during a year were missed by our methodology, otherwise we performed manual searches for the author's address.
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