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The direction and magnitude of reported brain differences depends on the methodology of data acquisition and analysis, whether and how the subcomponents are adjusted for the total brain volume difference, and the age of the participants in the studies.
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This study provides an example of data acquisition methodology that could be used in quantitative exposure studies of nanotechnology-based consumer products, especially when simulating realistic exposure scenarios.
The standardization of the methodology made it possible to define the samples evenly, recreating the same conditions of data acquisition for all the subjects.
AA participated in the design of the study's methodology and data acquisition and drafted the manuscript.
MMM advised on methodology and data acquisition and participated in the preparation of all drafts of the manuscript.
MMM advised on methodology and data acquisition and participated in the writing all drafts of the manuscript.
DBA participated in all parts of the work of the study (including the study design, methodology development, simulations, data acquisition, and manuscript drafting).
JWS was involved in conceptualizing the study, designing the methodology, data acquisition, analysis, data interpretation, and drafting of the manuscript.
This paper presents the methodology and description of the data acquisition of an asthma case-control study conducted in the Central South of Chile.
AL developed the study's methodology, participated in data acquisition and drafted the manuscript.
While the four areas of research differ in their scientific foundations, they nevertheless share a core set of informatics methodologies, such as data acquisition systems, controlled vocabularies, knowledge representation, simulation and modeling, information retrieval, and signal and image processing, which provide a basis for their intersection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com