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"The literature and the methodology have advanced.
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The experimental methodology has advanced, mainly on the basis of modified methods taken from electrode kinetics.
Clinical trial methodology has advanced with new disability measures, new MRI approaches for identifying destructive pathology, and new study designs.
Also, methodologies of clinical trials have advanced significantly as a consequence of the introduction of CSIs.
Post-genome methodologies, such as analysis of transcriptomes, proteomes, metabolomes and bioinformatics have advanced our understanding of seed germination.
Current methodologies for the detection and isolation of carcinogen-DNA adducts have advanced beyond the capabilities of the methods used to elucidate their structures.
Things have advanced since then.
Surgical techniques have advanced too.
The techniques have advanced hugely".
Rodents have advanced cognitive abilities.
The demand to improve HSC transplantation has advanced the methodology to expand HSC in vitro.
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