However, the SUV methodology has well-known shortcomings.
However, the SUV methodology has well-known shortcomings such as uptake time dependence of the SUV, unsatisfactory test/retest stability, susceptibility to errors in scanner calibration etc. [1 6] all of which adversely affect the reliability of the SUV as a surrogate of the metabolic rate of FDG (and ultimately of glucose consumption).
Our study relied on retrospective data analysis, a methodology that has well-known limitations.
DEM methodology has been well established but there is a lack of detailed validation of DEM models to experimental data and methods to calibrate and scale-up DEM models to attain accurate predictions and results.
Growth diagnostics methodology has been well established through the work of Hausman and Rodrick, among others, and has been widely applied, including in Kosovo.2 This is, effectively, an alternative to the econometric approach most commonly used in this kind of study.
Once again, our proposed methodology has performed well.
Our methodology has performed well, in that it provided results which are in agreement with intuition, by highlighting study 16 but not actually designating it an outlier.
This informal methodology has worked well because acceptability judgments of linguistic phenomena tend to be strikingly robust, even at very small sample sizes (for a large-scale quantitative evaluation, see Sprouse & Almeida, 2010).
As this methodology has been well-described in literature, the technique is described only briefly here (Komistek et al. 1998; Li et al. 2014).
To this end, we believe our SPECT/CT methodology has served its purpose well.
