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Examples of this approach have recently been published and represent a promising methodology for standardization of quantitative immunostaining assessment and fluorescence in situ hybridization (FISH) signal counting [ 17, 26].
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We therefore deem that our methodology for automated CLIFT standardization can be adapted to many laboratories, regardless of which equipment is used.
Was applied the methodology of the European Committee for Standardization, EN1499 version April 2013, indicated to evaluate the efficacy of antiseptics for hand hygiene.
This is likely due to technical differences, experimental design and diagnostic relevance of the biomarker identified, which highlights the need for methodology standardization and external validation [184].
Yet, criteria sets for standardization of methodology have been developed, initially by the EORTC PET study group (1999) 35 and latest with PERCIST (2009) by Wahl et al. 19, 36, applied in this study.
Box 3. Standardization of methodology for in vitro assays aside from GIA. Standardization of qPCR methodology and modeling of data across trial centers.
Guidance from the Institute for Quality and Efficiency in Health Care (IQWiG) on cost estimation in cost benefit assessments in Germany acknowledges the need for standardization of costing methodology.
In this document, it is acknowledged that there is potential for standardization of costing methodology to improve the comparability of health economic evaluations.
Cheminformatics and bioinformatics are extensively using predictive modelling and exhibit a need for standardization of these methodologies in order to assist model selection and speed up the process of predictive model development.
It is often stressed that standardization of the methodology for characterization of engineered tissues should be established for the promotion of tissue engineering.
These recommendations offered a starting point for the standardization of PET methodology for the use of FDG-PET as a biomarker for treatment response in clinical trials [ 12].
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