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The quality of the results produced by the methodology at each step of their calculation procedure was assessed and discussed, taking as reference the accurate results provided by the advanced approach, based on the application of the hybrid electromagnetic model (HEM) and disruptive effect model (DE).
Reticulocyte count, lactate dehydrogenase, aspartate aminotransaminase and total bilirubin were analyzed by automated methodology at each institution and used to develop the hemolytic component described in the Statistical analysis section below.
The isolates were identified at the participating hospitals by routine methodology at each laboratory, and then were transported to Beijing Children's Hospital for further analysis.
One possible mitigation is to heterogenize methodology at each site; however, the resulting variability is the natural enemy of smaller (genetic or other) modifications where behavioral phenotypes might be more subtle yet very informative [ 15].
Least squares (LS) effect size and standard errors (SEs) were calculated according to the method of Curtin, Altman, and Elbourne [ 28] (standardized weighted mean difference [SWMD] methodology) at each postdose time point for SKAMP and PERMP assessments and for mean SKAMP-D score in the ITT population.
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In the following, we discuss the methodology employed at each experiment.
A note: depending on the school, external scholarships might reduce need-based financial aid but the methodology is at each school's discretion.
The assessments were done as part of ARC's programming and while every attempt was made to have consistent methodology applied at each site, variations by site, as described above, occurred in the course of doing fieldwork.
The extraction of lipase from the fermented bran obtained in solid-state fermentation by the fungi Aspergillus niger was carried out by adding 10 mL buffer with pH established in each methodology at 1 g of fermented medium, followed by agitation of 160 min−1 for 30 min at 37°C.
We also maintain detailed documentation on each tool and methodology at http://docs.viramp.com.viramp.com
The patients were screened using methods applied at each local centre, but guidelines were available to ensure the use of similar methodology at all centres.
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