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Quantitative receptor profiling of patient samples would speed progress into personalized medicine methodologies, with significant advancement when the patient profiling is coupled to computational modeling platforms.
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To summarize, the contribution of this work is the proposal of a blind watermarking methodology with significant enhanced robustness under signal processing attacks and imperceptibility of high levels.
It is a cumbersome methodology with a significant number of steps, which need to be carried out to define a final short list of recommendations.
After the introduction and fundamental illustration of the structures and extraordinary properties, we discuss the significant developments in synthetic methodologies and energy conversion applications with significant strategies for enhancing catalytic performance.
However, the chosen methodology led to obvious biases with significant impact on the results, especially when long-term results are considered.
A multistage crystal structure prediction (CSP) methodology is applied to axitinib, a pharmaceutical molecule with significant polymorphism arising from molecular flexibility.
Our results show that the methodology of clinical trials changed substantially over the past 60 years, with significant improvement in quality reporting and in internal validity.
Modified: The indicator is submitted to the second round of rating with significant changes in the definition and/or methodology following the respondents' comments.
Our optimization methodology is best suited for designing future field surveys with a favorable benefit-cost ratio in areas with significant à priori knowledge.
The value of the remaining $17 billion is an estimate based on "internally developed models or methodologies utilizing significant inputs that are generally less readily observable".
A niche with significant potential.
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