The reason Ofcom is looking at data from, in some instances, almost two years ago is to ensure "data and methodologies are comparable across the selected member states", it said.
The Searle studies predated GLP standards but their methodology was comparable; transgenic mouse models are not validated, but are accepted as supporting data.
This proposed methodology is comparable to ASTM standards and can be used to study the effect of different biomaterial formulations as well as test parameters on the bone-to-bone adhesion strength, in a reproducible manner.
Conclusion: Endovenous vein obliteration without high ligation dramatically reduces the presence of varicosities and reflux and, when performed with the prescribed pull-back methodology, is comparable with vein stripping at 1 and 2 years.
Using Deming regression analysis, we show that results from both methodologies were statistically comparable.
Reprogramming efficiencies were comparable to viral methodologies (up to ~ 9-12%) without the constraints of capsid size and with the ability to control plasmid dosage, in addition to showing superior performance relative to existing non-viral methods.
The trials generally were comparable in their methodology, with the possible exception of the Cleary [ 47] trial.
It should be noted that the overall study methodology and population in this study were comparable to those of trials in preclinical AD, suggesting that appropriate computerized testing will at the minimum be no less sensitive than neuropsychological tests.
Using a standardized reporting methodology, we found the complications in this cohort were comparable with previous reports.
However, these methodologies were not fully comparable because they used a different adjustment variable – the adjustment variables were examined separately within variable-centred analyses, but were combined into a composite adjustment variable for person-centred analyses.
