Applying this simple investigative methodology, we demonstrated that this substance has a high buffering capacity and stability against perturbations, such as the addition of strong acids and strong bases.
Using this methodology, we demonstrated that about 65% of the active sites within PDI became oxidized within 2 min when incubated with PrxIV in the absence of GSH.
Applying this methodology, we demonstrated that lung adenocarcnomas with ALK fusion feature less amplification of loci with oncogenes and fewer deletions of loci related to tumour suppressor genes, although global chromosome aberrations were similar between tumours with and without ALK fusion.
By application of this methodology, we demonstrate that capital cost reductions of up to 28% are possible relative to a business-as-usual design case.
Using tracer methodology, we demonstrate that the HN-induced increase in glucose uptake is associated with increases in both glycolysis and glycogen synthesis (P<0.05, Figs. 2I & 2J).
With this improved methodology, we demonstrate that tRNA-dependent pretransfer editing contributes up to 30% of the overall IleRS editing.
Using a cross-validation methodology we demonstrate that both support vector machines (SVMs) and random forests (RFs) based methods produce recognition models that are significantly better than previously published methods.
Using a simple methodology (Fig. 7), we demonstrated that it is possible to generate human iPSCs at a high frequency without viruses and with no evidence of genomic insertion.
Thus, in performing these tests of the methodology, we have demonstrated that different methods will give different results and that some methods give results that do not agree with experimental data.
In this paper, we demonstrated the methodology with the van Genuchten water retention curve.
