Due to the complexity of PCR optimization, the risk of contaminant amplification, the presence of known or unknown PCR inhibitors in reaction mixtures, and the inherent replication error rate, the potential for misdiagnosis when using PCR based diagnostic methodologies is significant [15], [16].
In terms of methodologies utilized, there was significant variation in terms of the research designs applied.
Economic studies indicate that transmission lines employing optimized designs and scientific cost management methodologies for construction are significant in achieving much higher savings in capital investments.
Pooling of five twin studies results (excluding Danis and colleagues [27] due to different methodology) suggests there are significant pooled rMZ for absolute VO2max (L.min−1) (rMZ = 0.38, 95% CI: 0.04 0.64, n = 42) and relative VO2max (mL.min−1.kg−1) (rMZ = 0.39, 95% CI: 0.07 0.64, n = 48) (Table 4).
Implications for the FF life assessment methodology are found to be significant.
Therefore, when the two methodologies are compared, no significant variation was observed in the number of approved images, given that the greatest difference was of only two images.
As clinical MRSA diagnosis is concerned, current diagnostic methodologies are restricted by significant drawbacks and novel methods are required for MRSA detection.
Oncologists should be aware that, although HER2-testing methodologies are now numerous, significant differences exist between the various available tests, which may impact on patient safety as well as outcomes.
Models for oxides of nitrogen (NOx), smoke, brake thermal efficiency (BTE) and brake specific fuel consumption (BSFC) were developed using response surface methodology (RS M and were found to be significant statistically.
(ii) Optimum design is developed by applying Box Behnken Design (BBD) under response surface methodology (RS M for engineering application which is significant to guide the further industrial recycling process.
