Given the lack of methodologies that currently exist for routine monitoring of nanomaterials, he suggests that monitoring of silver itself in water, sediment, or biomonitors "could be a viable interim approach until methods specific to the nanomaterial are developed".
Though this study focused on the implementation of a government mandated program based on Lean principles, and not on an evaluation of Lean itself, it is important to acknowledge the critiques that exist towards Lean methodology and implementation [ 40- 42].
"We've built stuff nobody has built before with development process and methodologies that didn't exist," he said.
Future studies in primary hepatocyte cell cultures with emphasis on genomic pathways anchored to phenotypical changes in the MOA could add useful data in reducing the current uncertainty that exists in the TEF methodology.
10 No guidance exists to assess methodologies that lead to different results.
Several methodologies exist that allow the derivation of G Ic from this testing data, resulting from a linear elastic fracture mechanics analysis.
A strategic requirement exists to define a methodology that may be used to create a representative HP duty-cycle.
Because only three regions (out of 34 at the time of writing) were involved in the study, the details of the results are less relevant than that differences exist and that this methodology has the capacity to reveal them.
Note, however, that while multiple methodologies exist for classifying the synoptic-scale pattern at a specific location [ 29], it is imperative that any air-mass-based approach capture the synoptic-scale meteorological pattern to reduce the uncertainty in applying this methodology.
We designed a methodology that ensures that there exists a fit solution (CRM) for the target pattern under either function model, with and without the ubiquitous activator, so that any difference in time-to-evolve can be attributed to the evolutionary ramifications of the ubiquitous activator (see Materials and Methods).
