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Researching new treatments for patients with bipolar disorder presents specific problems not readily addressed by traditional efficacy trial methodologies that aim to maximize internal validity.
This has lead to the definition of two original assembly methodologies that aim to optimise an assembly, so that circularity errors are minimised for a given set of components.
This perspective article highlights the work of seven project teams developing first-in-class translational and quantitative methodologies that aim to inform drug development decision-making, dose selection, trial design, and safety assessments, in order to achieve shorter and safer therapies for patients in need.
I think it is important to mention other methodologies that aim to answer the same questions as those provided by network-based analyses.
MST includes a group of methodologies that aim to identify, and in some cases quantify, the dominant sources of fecal contamination in the environment and, more specifically, in water resources [ 10, 11].
Methodologies that aim to overcome resolution limits can provide deeper insights into finer structures of modules in complex networks and a more accurate depiction of community structure on the basis of the modularity measure.
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In the UK, the British Thoracic Society (BTS) and Scottish Intercollegiate Guidelines Network (SIGN) have produced a set of stepwise guidelines using evidence-based methodology that aim to eradicate symptoms as quickly as possible and optimize peak flow (BTS, SIGN 2007).
This paper presents a methodology that aims at the incremental representation of areas inside environments in terms of attractive forces.
The next section describes a methodology that aims at the incremental learning of environment properties based on moving agents' observations.
In this study, we applied a four-step methodology that aims to optimize the accuracy of MODIS snow data.
Ecological and Economic Zoning (EEZ) is a Land Use Planning (LUP) methodology that aims at defining separate areas for productive uses and conservation.
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