All emitted light intensity data were corrected for light attenuation effects following the methodology set out by Susanto et al. (30).
Of primary importance to the validity of the methodology set out here, the results obtained after a second randomisation were almost identical.
A roadmap calling for elimination of the trypanosomiases by 2020 27 will require improved diagnosis of these diseases, and the methodology set out here offers potential toward detecting parasites in low-parasitaemia infections.
The variables allowed to vary in the PSA, probability distributions and parameter values in the model are shown in Tables 1, 2, 3 and 4 and are chosen in line with the methodology set out in Briggs et al. [ 12].
Following the methodology set out by Linnet [ 19] for the calculation of sample size, the key would be the ratio between the width of reference range and the width of the confidence interval for the extremes of the said reference range.
Each time the cumulative load challenge reached one of the predefined amounts, the cycle in progress was allowed to run to completion, that is, the column washed, eluted, sanitized, and placed into storage buffer according to the methodology set out previously (Materials and Methods: AEX chromatography), and the AEX cycling paused.
This was a Phase II study based on the methodology set out in the Medical Research Council's guidelines for the evaluation of complex interventions[ 16] The pragmatic design builds on current evidence that there is a significant difference between acupuncture and sham acupuncture for this condition [ 9- 11].
One strength of our study is that it took into account potential sources of bias, such as autocorrelation, which often arise in the analysis of routine longitudinal data [ 25], and used the methodology set out in a recent Cochrane systematic review which concluded that more rigorous research on the effects of user fees on health-care utilisation was needed [ 6].
The methodology set out to examine the seasonal environment/health problem from hazard to outcome - combining analysis of changes in levels of environmental contamination, seasonal variations in disease incidence and a social scientific analysis of health behaviour in order to understand changing risk to public health.
The methodology sets out from a parametrisation of the gauge corner and the flange root geometries.
