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As the number of high-throughput methodologies has increased, so has the number of ways in which GO annotation data has been exploited to link experimental results to current functional knowledge.
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In the last 10 15 years, preclinical research methodologies have increased crucially regarding measurement of sensitivity and specificity.
Qualitative methodology has increased in application and acceptability in all research disciplines.
Study design has improved considerably over the years as application of rigorous scientific methodology has increased [ 20].
39 While the number of studies that use this methodology has increased rapidly in recent years, this type of design is known to have some limitations (Table 2).
SKAT [ 53] implements this methodology and has increased power to detect association if accurate prior 'functionality' weights can be assigned to the variants under consideration.
The use of design-based research methodology in educational contexts has increased over the past decade and mostly with educational technology innovations and interventions (Anderson and Shattuck 2012, p.25).
The use of Bayesian methodologies for solving optimal experimental design problems has increased.
Applying the methodology to European regions, they find that the short-term response of labour mobility has increased over time.
In particular, we focus on recent advancements in finite element methodology that have increased the fidelity of VAD simulations.
Improvements in sequencing chemistry, methodologies, hardware, and software have increased sequencing read quantity and length, improved multiplexing scalability, and added further robustness to genotyping calls [ 4, 5].
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