Sentence examples for methodologies for binding from inspiring English sources

Albeit other shape-based methodologies for binding site identification exist (e.g. Triform [ 14]; T-PIC [ 13]), MeDiChISeq presents further conceptual advantages originating from the training step that defines a "consensus" binding pattern, which is then used to identify significant binding events at genome-wide level.

Autodock has been employed successfully to perform a screen of ATP binding sites on the matrix-facing surface of ANT1, so we adopted similar methodologies for ADP binding in the cytosol-facing pocket.

32, 35 A brief overview of methodologies using the structural consensus approach can be found in Table 2. Unfortunately, as of yet there has been no large scale comparison of different methodologies for representing binding sites by incorporating structural profiles.

We here present novel methodology for computing binding free energies and their analytical dependence on chemical properties based on the so-called solute-solute equation of the reference interaction site model (RISM) [3].

For the set of alleles studied in this work, we found the DPPS encoding scheme to be efficient in conjunction with the proposed methodology for peptide binding classification.

In such circumstances, the MTLD could provide various binding sites as the training sets or testing sets for the development of novel methodologies for comparisons of binding sites.

Thirty years ago, originalism was dismissed as an outmoded interpretive methodology and stigmatized as a conservative strategy for binding us to the dead hand of the past.

Good correlation between both methods was observed, indicating that qPhage recapitulates a state-of-the-art methodology for phage-cell binding.

Taken together, these results suggest that N-ChIP-seq outperforms current X-ChIP methodologies for genome-wide profiling of TF binding sites.

In the realm of using label-free small molecules for binding target identification, another affinity-based label-free methodology was introduced in 2010 (109).

However, the lack of experimentally verified AtoC binding targets other than that upstream of the atoDAEB promoter [ 5], necessitates the utilization of bioinformatics methodologies for the task of predicting potential AtoC binding motifs.