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All these methodologies can, in principle, be combined with the imaging and processing strategy reported here.
Thus, such methodologies can, in principle, provide posterior estimates for indel dynamics parameters.
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The numerical results show that the traditional excogitation methodology can in general give a favorable outcome with higher reliability.
With substitution of other hydrolytic enzyme preparations in place of Driselase, the methodology can in principle be applied to polysaccharide and other potential polymeric OH targets isolated from a wide range of animal, plant and microbial sources in which interesting cases of polysaccharide cleavage are thought to be occurring.
Orthogonal global analysis using different methodologies can assist in enriching for candidate driver genes and pathways.
In both cases we comment on the application of the respective risk assessment, risk mitigation and validation steps and how both in silico and suitable surrogate or proxy in vitro methodologies can be combined in a unified workflow.
We specify how different analysis methodologies can be integrated in our framework.
We discuss why MBSE methodologies can be valuable in assessment of PPS.
Detailed descriptions of PhyloChip construction, validation and methodologies can be found in Brodie et al. [17], [18].
All identified studies were included because even studies with less rigorous methodologies can be valuable in the synthesis process [ 29].
Non-hierarchical methodologies can only compete in this measure if a family includes no more than one duplication per lineage.
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