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Subsequently, this resource has been optimized and completed: the size of the genomic clones has been expanded to a target size of 100 200 kb, which is optimal for use in genome-scanning methodologies, and additional probes for the remaining seven telomeres have been identified.
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As a result, the IMRFs do not attain the collapse performance required by FEMA P-695 methodology, and additional design requirement adjustments would be needed to improve the overall performance.
(XLSX 2590 kb) Additional file 2: Supplementary file outlining the detailed sequencing methodology and additional figures.
There is also information available for each indicator which provides the relevant definition, methodology and additional comments.
We contacted study authors by email, with a reminder after 1 month, for clarifications, additional information about methodology, and additional subgroup analyses where necessary.
We have not been able to adequately define this clustering; doing so would likely require new statistical methodology and additional variables and observations.
We found that the four gene categories had a different number of enriched pathways using Kyoto Encyclopedia of Genes and Genomes (KEGG) (see Methodology and Additional file 4).
We contacted study authors by e-mail for clarifications, additional information about methodology, and for additional subgroup analyses where necessary.
The stages involved are shown in Figure 2 where we see the general prediction methodology and the additional route for the interpretation of a prediction.
The coding was carried out by senior research assistants who had graduate training in research methodology, and received additional training in HCV epidemiology, drug use and meta-analytic methods.
In order to test our preliminary framework and to reach consensus for the inclusion of each item, the reporting framework was pilot tested against forty published syntheses of qualitative research, which were purposively selected from our search results to capture a range of year of publication, methods and methodologies, and health topics (Additional file 3).
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CEO of Professional Science Editing for Scientists @ prosciediting.com