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The herein proposed methodologies allow the reliable determination of very low nanoparticle concentrations.
The information obtained here is valuable to be considered for upcoming comparability studies of biosimilars, since current state-of-the-art analytical methodologies allow the assessment of relevant quality attributes related to the safety and efficacy.
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All methodologies allowed the recommendations of the official methods.
Furthermore, the proposed methodologies allowed the determination of the CdSe QDs diameters.
Imaging mass spectrometry coupled to peptidomic and lipidomic methodologies allowed the selection of molecules whose spatiotemporal pattern of expression was of potential interest.
Nowadays, the extensive use of different high-throughput methodologies allows the obtention of different measurements for the genes such as methylation status, splicing variants, linkage to diseases, etc., in a straightforward manner.
Extensive purification of blad and sequencing of its N- and C- terminals, as well as of several internal sequences by conventional methodologies allowed the precise location of the nucleotide sequence encoding blad within that of its precursor (Figure 1).
Therefore, applying these methodologies allows the selection of causal structures without relying on prior knowledge alone.
Combining the results of both methodologies allowed the estimation of the incidence of post-F1 hybridisation and back-crossing.
In this context, there is an obvious need for methodologies allowing the low-cost, fast and high-throughput genotyping of virtually any species, such as the Diversity Arrays Technology (DArT).
In this context, there is an obvious need for new methodologies allowing the low-cost, fast and high-throughput genotyping of virtually any species.
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