The review suggests a need for methodologically sound research that translates simulation outcomes to future performance and practice.
Developing methodologically sound measures of assessing REC outcomes is an area ripe for further research.
As a consequence, the outcomes gathered from rigorous and methodologically sound trials may not be generalizable to users within the community.
[T]he most careful, rigorous, and methodologically sound study ever conducted on this issue found numerous and significant differences between these groups -- the outcomes for children of homosexuals rated "suboptimal" (Regnerus' word) in almost every category.
At best, these kinds of methodologically sound evaluation studies show the effect of a measure in a given situation.
The reference criteria for confirmation of growth restriction and compromise of wellbeing are different and our project will deal with this issue in a methodologically sound manner.
By following guidelines for patient-reported outcome instrument development and in cooperation with clinical and methodological experts in five countries, a comprehensive, methodologically sound and practical instrument was developed, which can be used for clinical research as well as a tool to evaluate treatment benefits in a practice environment.
The most important finding of this review is the lack of methodologically sound intervention studies on breast cancer survivors with the outcome return to work.
10 15 Our previous review 9 found only 15 methodologically sound studies, and, of these, only two provided information on outcomes beyond three months.
The strengths of our analysis are that we analysed a large number of individual patient data in a clinically important chronic pain condition, using validated instruments for measuring clinically important trial outcomes, based on large, modern, rigorous, and methodologically sound trials.
