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By following guidelines for patient-reported outcome instrument development and in cooperation with clinical and methodological experts in five countries, a comprehensive, methodologically sound and practical instrument was developed, which can be used for clinical research as well as a tool to evaluate treatment benefits in a practice environment.
Substudies of cardiovascular end point trials and mechanistic studies should be methodologically sound and designed to test specific models.
Despite the excitement of the previous evidence from laboratory, animal and observational studies, and the plausibilty of the explanation of how beta carotene might work inside the human body, the clinical trials were methodologically sound and large enough to leave little uncertainty about their conclusions.
More importantly, it is methodologically sound, and its reliability and validity are backed up by clear evidence.
The editors of this journal screen the top 100+ clinical journals and identify studies that are methodologically sound and clinically relevant.
But, they added, their surveys are transparently executed and methodologically sound, and they offer revealing glimpses on how Americans see themselves.
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It is attentive to all the relevant issues and bibliography, methodologically sound, clearly and carefully argued, but also boldly original.
10 15 Our previous review 9 found only 15 methodologically sound studies, and, of these, only two provided information on outcomes beyond three months.
Citations were checked to see that they were of methodologically sound research, and could be validly generalised to the particular telehealth setting, to determine whether a cost-minimisation analysis could be undertaken.
By means of a methodologically sound translation and an adaptation process, we were able to transform a published international questionnaire for measuring CAM use (I-CAM-Q) into a German version of the measurement instrument (I-CAM-G).
Objective: the complete overhaul of FAO statistical database with more reliable, methodologically-sound and transparent data and new aggregations and extrapolations functions, providing decision makers with improved data series, therefore, contributing to improved planning, evaluation and policy setting in countries.
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methodologically accurate and
methodologically diverse and
methodologically satisfactory and
methodologically poor and
methodologically robust and
methodologically consistent and
methodologically broad and
methodologically inferior and
methodologically adequate and
methodologically insufficient and
methodologically unsound and
methodologically weak and
methodologically rich and
methodologically defective and
methodologically limited and
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com