Sentence examples for methodologically rigorous RCTs from inspiring English sources

Methodologically rigorous RCTs must be designed to overcome these serious threats to internal validity.

A lack of awareness of bias and negative attitudes towards research present significant barriers in terms of conducting methodologically rigorous pediatric RCTs.

A previous mixed-methods study of pediatric trialists identified a lack of research training, negative research culture and logistical challenges as barriers to conducting methodologically rigorous pediatric RCTs [ 22].

We used this reporting quality assessment tool as our reference standard due to its widespread use [ 15] and association with the methodologically rigorous Cochrane reviews of RCTs [ 9, 16, 17].

There is a need to develop a robust methodology to perform methodologically rigorous and transparent cost of illness studies to inform policy decisions.

We were able to demonstrate a statistically significant improvement in clinical outcomes (reduced clinical failure rates) and ICU LOS, even when exclusively methodologically more-rigorous RCT data are pooled.

In this study scientific evidence refers to methodologically rigorous research, such as randomized controlled trials (RCTs).

In an attempt to clarify the comparative effect of prolonged versus intermittent infusion β-lactam antibiotics on mortality, clinical cure, and adverse effects, we analyzed RCTs that offered the most methodologically rigorous evidence from the available studies.

For interventions with several published RCTs (e.g. psychosocial interventions), results from less methodologically rigorous studies were not presented.

The RCT by Schwarz et al. [19] appeared to be the most methodologically rigorous but was still rated unclear since only the study protocol and abstract were available for assessment.

Few RCTs have tested the effects of moxibustion for UC, and none of the existing trials were methodologically rigorous.